Drug name: Welireg

  • Original languages: en en en English

Description:

Welireg

Generic name: belzutifan
Dosage form: tablets
Drug class: Miscellaneous antineoplastics

Medically reviewed by Judith Stewart, BPharm. Last updated on Oct 1, 2021.

What is Welireg?

Welireg is a prescription medicine used to treat adults with von Hippel-Lindau (VHL) disease who need treatment for a type of kidney cancer called renal cell carcinoma (RCC), tumors in the brain and spinal cord called central nervous system hemangioblastomas, or a type of pancreatic cancer called pancreatic neuroendocrine tumors, that do not require surgery right away.

It is not known if this medicine is safe and effective in children.

Important information

Welireg may cause serious side effects, including:

  • Low red blood cell counts (anemia). Low red blood cell counts are common with Welireg and can be severe. You may need a blood transfusion if your red blood cell counts drop too low. Your healthcare provider will do blood tests to check your red blood cell counts before you start, and during treatment. Tell your healthcare provider if you get any symptoms of low red blood cell counts, including tiredness, feeling cold, shortness of breath, chest pain, or fast heartbeat.
  • Low oxygen levels in your body. Welireg can cause low oxygen levels in your body that can be severe and may require you to stop treatment, receive oxygen therapy, or be hospitalized. Your healthcare provider will monitor your oxygen levels before you start, and during treatment. Tell your healthcare provider or get medical help right away if you get symptoms of low oxygen in your body, including shortness of breath or increased heart rate.
  • Harm to your unborn baby. Treatment with Welireg during pregnancy can cause harm to your unborn baby.
    Females who are able to become pregnant:
    • Your healthcare provider will do a pregnancy test before you start treatment with Welireg.
    • You should use an effective form of non-hormonal birth control (contraception) during treatment, and for 1 week after your last dose.
    • Birth control methods that contain hormones (such as birth control pills, injections, or transdermal system patches) may not work as well during treatment with Welireg.
    • Talk to your healthcare provider about birth control methods that may be right for you during treatment with Welireg.
    • Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment.

Males with female partners who are able to become pregnant:

    • You should use effective birth control (contraception) during treatment with Welireg and for 1 week after your last dose.
    • Tell your healthcare provider right away if your partner becomes pregnant or thinks she is pregnant while you are taking Welireg.

See Welireg side effects for more information about side effects.

Before taking Welireg

Before taking Welireg, tell your healthcare provider about all of your medical conditions, including if you:

  • have low red blood cell counts (anemia)
  • are pregnant or plan to become pregnant. See Important information.
  • are breastfeeding or plan to breastfeed. It is not known if Welireg passes into your breast milk. Do not breastfeed during treatment, and for 1 week after your last dose.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Welireg and certain other medicines can affect each other and cause serious side effects.

Know the medicines you take. Keep a list of them to show to your healthcare provider and pharmacist when you get a new medicine.

Welireg pregnancy and breastfeeding warnings (more detail)

How should I take Welireg?

  • Take Welireg exactly as your healthcare provider tells you.
  • Do not stop taking Welireg or change your dose without talking to your healthcare provider.
  • Take your prescribed dose of Welireg one time a day, at the same time each day.
  • Your healthcare provider may change your dose, temporarily stop, or permanently stop treatment if you have certain side effects.
  • Take Welireg tablets with or without food.
  • Swallow the tablets whole. Do not chew, crush, or split the tablets.
  • If you miss a dose, take it as soon as possible on the same day. Then take your next dose at your regular time the next day. Do not take extra tablets to make up for the missed dose.
  • If you vomit after taking a dose, do not take an extra dose. Take your next dose at your regular time the next day.
  • If you take too much or overdose, call your healthcare provider or go to the nearest emergency room right away.
Detailed Welireg dosage information

Welireg side effects

Welireg may cause serious side effects, including:

  • See Important information

The most common side effects include:

  • feeling tired
  • increased creatinine (kidney function test)
  • headache
  • feeling dizzy
  • increased blood sugar (glucose) levels
  • nausea

Welireg may cause fertility problems in males and females, which may affect your ability to have children. Talk to your healthcare provider if this is a concern for you.

These are not all the possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Welireg side effects (more detail)

What other drugs will affect Welireg?

Many drugs can interact with belzutifan, and some drugs should not be used at the same time. Tell your doctor about all other medicines you use. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

Welireg drug interactions (more detail)

How should I store Welireg?

  • Store Welireg at room temperature between 68°F to 77°F (20°C to 25°C).
  • The Welireg bottle contains 2 desiccant canisters that help keep your medicine dry. Do not eat the desiccant canisters.

Keep all medicines out of the reach of children and pets.

General information about the safe and effective use of Welireg

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use this medicine for a condition for which it was not prescribed. Do not give it to other people, even if they have the same symptoms you have. It may harm them. You can ask your pharmacist or healthcare provider for information that is written for health professionals.

What are the ingredients in Welireg?

Active ingredient: belzutifan
Inactive ingredients: croscarmellose sodium, hypromellose acetate succinate, magnesium stearate, mannitol, microcrystalline cellulose, and silicon dioxide. The film-coating contains FD&C Blue #2 aluminum lake, polyethylene glycol, polyvinyl alcohol, talc, and titanium dioxide.

More about Welireg (belzutifan)

  • Check interactions
  • Pricing & coupons
  • Drug images
  • Side effects
  • Dosage information
  • During pregnancy
  • FDA approval history
  • Drug class: miscellaneous antineoplastics
  • En español

Professional resources

  • Prescribing Information

Related treatment guides

  • Von Hippel-Lindau Syndrome

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

','2023-03-10 20:59:03','2023-03-10 20:59:03'); INSERT INTO `default`.drags_translation (drag_id,language_id,title,content,created_at,updated_at) VALUES (15412,3,'Wellbaby DHA','

Wellbaby DHA

Generic Name: Omega 3 supplement

Brand Names: Wellbaby DHA-Vitamin D3

Medically reviewed by C.Fookes BPharm. Last updated on March 12, 2019.

What is Wellbaby DHA-Vitamin D3

Wellbaby DHA-Vitamin D3 is an oral omega 3 plus vitamin D supplement that has been formulated to support a young baby’s diet. Wellbaby DHA-Vitamin D3 contains DHA and vitamin D3 at levels recommended by the UK Department of Health.

DHA (docosahexaenoic acid) is an Omega-3 fatty acid. Omega-3 fatty acids are essential for human health, but the human body can’t make them, so they must be obtained through diet or supplementation. DHA is found in high amounts in the tissues of the brain, skin, and eye, and babies accumulate a large amount of DHA during their first year of life.

Vitamin D which is needed for normal growth and development of bone in children. It also contributes to their normal immune system function.

During their early years, children''s nutritional requirements are particularly high. Wellbaby DHA-Vitamin D3 helps support general health and wellbeing in babies.

Important Information

Take Wellbaby DHA-Vitamin D3 exactly as directed on the label, or as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended.

Wellbaby supplements are:

  • Free from peanut oil
  • Contain no artificial sweeteners, colours or flavour
  • Contain no salt, yeast, alcohol or lactose.

Wellbaby supplements are not tested on animals and are suitable for vegetarians. They have been specially formulated for babies and young children and are not recommended for adults.

Do not use if the bottle seal is broken on purchase. Use the dropper provided.

Once opened use within 3 months.

Wipe any spillage off your infant''s skin.

As with other food supplements, seek professional advice if your child is under medical supervision or suffers from food allergies.

Keep out of reach of children.

Store below 25°C in a dry place. To open bottle, press & turn childproof cap. Keep tightly closed. For Best Before end date, see the base of the carton.

Before Giving Your Baby Wellbaby DHA-Vitamin D3

Seek professional advice if your child is under medical supervision, has liver disease or a clotting disorder, has an upcoming surgery or a procedure that might increase their risk for bleeding, or suffers from food allergies. Be sure to check the label on Wellbaby DHA-Vitamin D3 to look for other active or inactive ingredients that may cause an allergy. If you are not sure, ask your pharmacist.

Wellbaby DHA-Vitamin D3 is a supplement and is not intended to take the place of a nutritionally-balanced diet that is recommended by experts for babies and young children.

What Happens if I Miss a Dose?

Give the missed dose as soon as you remember. Skip the missed dose if it is almost time for the next scheduled dose. Do not give extra medicine to make up the missed dose.

What Happens if I Overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What are the Side Effects of Wellbaby DHA-Vitamin D3?

Stop using Wellbaby DHA-Vitamin D3 and get emergency medical help if you think you have given too much medicine, or if your baby has any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious Wellbaby DHA-Vitamin D3 side effects may include:

  • Bad breath
  • Loose stools.

Less serious side effects are more likely, and your baby may have none at all. Talk to your doctor about any side effect that seems unusual or is especially bothersome.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

What other drugs will affect Wellbaby DHA-Vitamin D3?

Other drugs may interact with omega-3 polyunsaturated fatty acids, such as DHA, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all the medicines your baby needs and any new medicine you start or stop giving to your baby.

Your pharmacist or physician can provide more information about Wellbaby DHA-Vitamin D3.