Description:

13c urea and citric acid (Oral)

Commonly used brand name(s)

In the U.S.

IDkit Hp

Available Dosage Forms:

Tablet
Powder

Uses for 13c urea and citric acid

13C urea and citric acid are medicines used in a diagnostic test called Exalenz BreathID® non-invasive breath test. It is a test that analyzes a breath sample before and after taking 13C-enriched urea to help diagnose patients with infections in the stomach caused by a bacteria called H. pylori.

Both of these medicines are taken by the mouth. If any H. pylori bacteria are present in the stomach, they will cause the 13C urea to be broken down into carbon dioxide gas. When you breathe out by the mouth, the amount of carbon dioxide can be measured by Exalenz BreathID® Hp System to detect whether the bacteria are in your stomach.

These medicines are available only with your doctor''s prescription.

Before using 13c urea and citric acid

In deciding to use a diagnostic test, any risks of the test must be weighed against the good it will do. This is a decision you and your doctor will make. Also, other things may affect test results. For this test, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to 13c urea and citric acid or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of 13C urea and citric acid in the pediatric population. Safety and efficacy have not been established.

Geriatric

No information is available on the relationship of age to the effects of 13C urea and citric acid in geriatric patients.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this diagnostic test, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Receiving this diagnostic test with any of the following medicines is not recommended. Your doctor may decide not to use this diagnostic test or change some of the other medicines you take.

Aclidinium
Amantadine
Amiloride
Amitriptyline
Amoxapine
Anisotropine
Atropine
Belladonna
Benztropine
Biperiden
Bornaprine
Brompheniramine
Butylscopolamine
Canrenoate
Canrenone
Carbinoxamine
Carisoprodol
Chlorpheniramine
Chlorpromazine
Cimetropium
Clemastine
Clidinium
Clomipramine
Clozapine
Cyclobenzaprine
Cyclopentolate
Cyproheptadine
Darifenacin
Desipramine
Dicyclomine
Dimenhydrinate
Diphenhydramine
Doxepin
Emepronium
Eplerenone
Fesoterodine
Flavoxate
Fluphenazine
Glycopyrrolate
Glycopyrronium Tosylate
Homatropine
Hydroxyzine
Hyoscyamine
Imipramine
Ipratropium
Isopropamide
Loxapine
Mebeverine
Meclizine
Mepenzolate
Methantheline
Methixene
Methscopolamine
Nortriptyline
Olanzapine
Orphenadrine
Oxitropium Bromide
Oxybutynin
Paroxetine
Perphenazine
Pimozide
Pinaverium
Pipenzolate Bromide
Pirenzepine
Prochlorperazine
Procyclidine
Promethazine
Propantheline
Propiverine
Protriptyline
Quetiapine
Revefenacin
Scopolamine
Solifenacin
Spironolactone
Stramonium
Terodiline
Thioridazine
Thiothixene
Tiotropium
Tizanidine
Tolterodine
Triamterene
Trifluoperazine
Trihexyphenidyl
Trimethobenzamide
Trimipramine
Tropicamide
Trospium
Umeclidinium
Valethamate

Receiving this diagnostic test with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Aceclofenac
Acemetacin
Aliskiren
Amtolmetin Guacil
Aspirin
Azilsartan
Azilsartan Medoxomil
Benazepril
Bromfenac
Bufexamac
Candesartan
Captopril
Celecoxib
Choline Salicylate
Cilazapril
Clonixin
Dexibuprofen
Dexketoprofen
Diclofenac
Diflunisal
Dipyrone
Droxicam
Enalapril
Enalaprilat
Eprosartan
Etodolac
Etofenamate
Etoricoxib
Felbinac
Fenoprofen
Fepradinol
Feprazone
Floctafenine
Flufenamic Acid
Flurbiprofen
Fosinopril
Ibuprofen
Indomethacin
Irbesartan
Ketoprofen
Ketorolac
Lisinopril
Lornoxicam
Losartan
Loxoprofen
Lumiracoxib
Meclofenamate
Mefenamic Acid
Meloxicam
Moexipril
Morniflumate
Nabumetone
Naproxen
Nepafenac
Niflumic Acid
Nimesulide
Nimesulide Beta Cyclodextrin
Olmesartan
Oxaprozin
Oxyphenbutazone
Parecoxib
Perindopril
Phenylbutazone
Piketoprofen
Piroxicam
Pranoprofen
Proglumetacin
Propyphenazone
Proquazone
Quinapril
Ramipril
Rofecoxib
Salicylic Acid
Salsalate
Sodium Salicylate
Spirapril
Sulindac
Telmisartan
Tenoxicam
Tiaprofenic Acid
Tolfenamic Acid
Tolmetin
Trandolapril
Valdecoxib
Valsartan
Zofenopril

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper use of 13c urea and citric acid

Exalenz BreathID® non-invasive breath test is a diagnostic test that analyzes a breath sample before and after taking 13C-enriched urea to help identify patients with H. pylori infection.

Your doctor will start the breath test by collecting your breath samples using the BreathID® Hp device. You will drink a mixed solution of 13C-urea tablet and citric acid powder. You must drink the solution within 2 hours after mixing it. Then, you have to breathe normally via the cannula while the test is being performed.

Do not eat for at least 1 hour before taking the mixed solution.

If the mixed solution has large particles after mixing it for 5 minutes, do not use it and open a new kit.

Precautions while using 13c urea and citric acid

If you are taking antibiotics, proton pump inhibitors (eg, omeprazole, lansoprazole), or medicines containing bismuth, these may interact with the test. Your doctor will ask you to stop taking them for at least 2 weeks before the test.

13c urea and citric acid side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Incidence not known

Fast heartbeat
fever
hives, itching, or rash
hoarseness
irritation
joint pain, stiffness, or swelling
redness of the skin
swelling of the eyelids, face, lips, hands, or feet
tightness in the chest
troubled breathing or swallowing

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Drug name: 13c urea and citric acid (Oral)