Cystex Urinary Pain Relief

Generic name: methenamine and sodium salicylate [ meth-EN-a-meen-and-SOE-dee-um-sa-LIS-i-late ]
Drug class: Urinary anti-infectives

Medically reviewed by Drugs.com on Nov 7, 2022. Written by Cerner Multum.

What is Cystex Urinary Pain Relief?

Methenamine helps slow the growth of bacteria. Sodium salicylate is a pain reliever and a nonsteroidal anti-inflammatory drug (NSAID) in a group of drugs called salicylates (sa-LIS-il-ates).

Cystex Urinary Pain Relief is a combination medicine that is used to relieve symptoms of bladder infection or irritation, such as painful or burning urination, or feeling an urgent or more frequent need to urinate.

Cystex Urinary Pain Relief may help slow the progress of a bladder infection. Consult your doctor to make sure you do not need a prescription antibiotic medicine.

Cystex Urinary Pain Relief may also be used for purposes not listed in this medication guide.

Warnings

This medicine can increase your risk of fatal heart attack or stroke. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). This medicine may also cause stomach or intestinal bleeding, which can be fatal.

Before taking this medicine

An NSAID can increase your risk of fatal heart attack or stroke, even if you don''t have any risk factors. Do not use Cystex Urinary Pain Relief just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

An NSAID may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using Cystex Urinary Pain Relief, especially in older adults.

You should not use this medicine if you are allergic to methenamine, sodium salicylate, or aspirin.

Ask a doctor before using Cystex Urinary Pain Relief to treat painful or frequent urination if you''ve never had these symptoms before.

Ask a doctor or pharmacist if this medicine is safe to use if you have ever had:

• heartburn, stomach ulcers or bleeding;

• heart disease, high blood pressure;

• cirrhosis or other liver disease;

• if you are on a low-salt diet; or

• if you drink more than 3 alcoholic beverages per day.

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

If you are pregnant, you should not take this medicine unless your doctor tells you to. Taking an NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy.

Do not give Cystex Urinary Pain Relief to a child younger than 12 without medical advice. Do not give this medicine to a child or teenager with a fever, flu symptoms, or chickenpox. Salicylates can cause Reye''s syndrome, a serious and sometimes fatal condition in children.

How should I take Cystex Urinary Pain Relief?

Use exactly as directed on the label, or as prescribed by your doctor.

Use the lowest dose that is effective in treating your condition.

Take this medicine with a full glass of water.

Drink plenty of water each day.

Call your doctor if your symptoms do not improve after 3 days.

Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Cystex Urinary Pain Relief?

Ask a doctor or pharmacist before using other medicines for pain, fever, swelling, or cold/flu symptoms. They may contain ingredients similar to Cystex Urinary Pain Relief (such as aspirin, ibuprofen, ketoprofen, or naproxen).

Avoid alcohol. Heavy drinking can increase your risk of stomach bleeding.

Cystex Urinary Pain Relief side effects

Get emergency medical help if you have signs of an allergic reaction: sneezing, runny or stuffy nose; wheezing or trouble breathing; hives; swelling of your face, lips, tongue, or throat.

Cystex Urinary Pain Relief may cause serious side effects. Stop using Cystex Urinary Pain Relief and call your doctor at once if you have:

• ringing in your ears;

• a light-headed feeling, like you might pass out;

• new or worsening stomach pain; or

• bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.

Less serious side effects may be more likely, and you may have none at all.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Cystex Urinary Pain Relief?

Ask a doctor or pharmacist before using Cystex Urinary Pain Relief with any other medications, especially:

• a diuretic or "water pill";

• medicine to treat gout or arthritis;

• insulin or oral diabetes medicine; or

• a blood thinner--warfarin, Coumadin, Jantoven.

This list is not complete. Other drugs may affect Cystex Urinary Pain Relief, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Copyright 1996-2023 Cerner Multum, Inc. Version: 1.01.

CYSTO-CONRAY (Injection)

Generic name: iothalamate meglumine (injection route) [ eye-oh-THAL-a-mate-MEG-loo-meen ]
Drug class: Ionic iodinated contrast media

Medically reviewed by Drugs.com. Last updated on Jan 23, 2023.

Commonly used brand name(s)

In the U.S.

• CONRAY
• CONRAY-30
• CONRAY-43
• CYSTO-CONRAY

Available Dosage Forms:

• Solution

Therapeutic Class: Radiological Ionic Contrast Media

Uses for CYSTO-CONRAY

Iothalamate meglumine injection is used to help diagnose or find problems in the brain, back, heart, head, blood vessels, stomach, joints, pancreas, bladder, and other parts of the body. It is an iodinated contrast agent. Contrast agents are used to create a clear picture of the different parts of the body during certain medical procedures (eg, CT scans).

This medicine is to be given only by or under the supervision of a doctor.

Before using CYSTO-CONRAY

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of iothalamate meglumine in children. Some children may have more unwanted side effects which may require caution in patients receiving iothalamate meglumine.

Geriatric

No information is available on the relationship of age to the effects of iothalamate meglumine injection in geriatric patients.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Metformin

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other medical problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Allergy to a contrast agent, history of or
• Asthma—Use with caution. May increase risk of having allergic reactions.

• Heart or blood vessel disease or
• Hypertension (high blood pressure) or
• Hyperthyroidism (overactive thyroid) or
• Kidney disease, severe or
• Liver disease or
• Pheochromocytoma (adrenal problem) or
• Sickle cell anemia (inherited blood disorder)—Use with caution. May make these conditions worse.

• Homocystinuria (genetic disease)—Patients with this condition should avoid undergoing angiography because of the increase risk of having blood clotting problem.

• Congestive heart failure or
• Dehydration or
• Diabetes or
• Kidney disease or
• Multiple myeloma (cancer of plasma cells)—May increase risk of having kidney failure.

Proper use of CYSTO-CONRAY

This section provides information on the proper use of a number of products that contain iothalamate meglumine. It may not be specific to CYSTO-CONRAY. Please read with care.

A doctor or other trained health professional will give you or your child this medicine in a hospital. This medicine is given through a needle placed in an artery or a vein.

Drink extra fluids so you will pass more urine while you are receiving this medicine. This may help prevent kidney problems.

Your doctor may also give you medicines (eg, allergy medicine, steroids) to help prevent allergic reactions.

Precautions while using CYSTO-CONRAY

It is very important that your doctor check your or your child''s progress closely while you are receiving this medicine to see if the medicine is working properly and to decide if you should continue to receive it. Blood and urine tests may be needed to check for any unwanted effects.

This medicine may cause heart attack, stroke, and blood clotting problems. Tell your doctor right away if you or your child has chest pain that may spread to your arms, jaw, back, or neck, trouble breathing, nausea, unusual sweating, faintness, coughing up blood, numbness or weakness in your arm or leg, or on one side of your body, sudden or severe headache, or problems with vision, speech, or walking after receiving this medicine.

Check with your doctor right away if you have bloody urine, a decrease in frequency or amount of urine, an increase in blood pressure, increased thirst, loss of appetite, lower back or side pain, nausea, swelling of the face, fingers, or lower legs, trouble breathing, unusual tiredness or weakness, vomiting, or weight gain. These could be symptoms of a serious kidney problem.

This medicine may cause hypothyroidism (underactive thyroid) in children 3 years of age and younger. Check with your doctor right away if your child has depressed mood, dry skin and hair, feeling cold, hair loss, hoarseness or a husky voice, muscle cramps and stiffness, slowed heartbeat, weight gain, or unusual tiredness or weakness.

Serious skin reactions , including Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (DRESS), and acute generalized exanthematous pustulosis can occur with this medicine. Check with your doctor right away if you have black, tarry stools, blistering, peeling, or loosening of the skin, chest pain, chills, cough, diarrhea, fever, itching, joint or muscle pain, painful or difficult urination, red irritated eyes, red skin lesions, often with a purple center, sore throat, sores, ulcers, or white spots in the mouth or on the lips, swollen glands, unusual bleeding or bruising, or unusual tiredness or weakness.

Tell your doctor right away if you or your child has mild, burning pain, feeling of warmth or coldness, peeling of the skin, redness, or swelling at the injection site.

While using this medicine, you may be exposed to radiation. Talk with your doctor if you have concerns about this.

Make sure any doctor or dentist who treats you knows that you are using iothalamate meglumine injection. This medicine may affect the results of certain medical tests.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. You should not receive iohexol injection together with a steroid medicine into your spinal cord.

CYSTO-CONRAY side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

• Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
• bluish color of fingernails, lips, skin, palms, or nail beds
• chest pain or tightness
• cough
• coughing that sometimes produces a pink frothy sputum
• feeling of warmth
• increased sweating
• noisy breathing
• not breathing
• pale skin
• redness of the face, neck, arms and occasionally, upper chest
• swelling in the legs and ankles
• trouble breathing

Rare

• Changes in skin color, pain, tenderness, or swelling of the foot or leg
• chest discomfort
• dizziness
• fainting
• fast, slow, or irregular heartbeat
• lightheadedness
• pounding or rapid pulse
• stopping of the heart
• unconsciousness

Incidence not known

• Black, tarry stools
• blistering, peeling, or loosening of the skin
• blue-green to black skin discoloration
• bruising
• burning, crawling, itching, numbness, prickling, "pins and needles" , or tingling feelings
• chills
• collection of blood under the skin
• constipation
• deep, dark purple bruise
• depressed mood
• diarrhea
• dry mouth
• dry skin and hair
• feeling cold
• hair loss
• hoarseness or husky voice
• itching
• joint or muscle pain
• large, flat, blue or purplish patches in the skin
• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• muscle cramps and stiffness
• nervousness
• painful or difficult urination
• partial or slight paralysis
• problems with speech or speaking
• red irritated eyes
• red skin lesions, often with a purple center
• seizures
• sensitivity to heat
• sneezing
• sore throat
• sores, ulcers, or white spots in the mouth or on the lips
• sweating
• swollen glands
• trouble sleeping
• unusual bleeding or bruising
• unusual tiredness or weakness
• weight gain
• weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer