Generic name: clonazepam (oral route) [ kloe-NAZ-e-pam ]
Drug classes: Benzodiazepine anticonvulsants, Benzodiazepines

Medically reviewed by Drugs.com. Last updated on Sep 28, 2022.

Commonly used brand name(s)

In the U.S.

• KlonoPIN
• KlonoPIN Wafers

In Canada

• Accel-clonazePAM
• APO-clonazePAM
• Clonapam
• CO-clonazePAM
• DOM-clonazePAM
• Mylan-clonazePAM
• PRO-clonazePAM
• Riva-clonazePAM
• Rivotril
• Sandoz-clonazePAM
• Teva-clonazePAM
• Zym-clonazePAM

Available Dosage Forms:

• Tablet, Disintegrating
• Tablet

Therapeutic Class: Antianxiety

Pharmacologic Class: Benzodiazepine, Short or Intermediate Acting

Uses for Zym-clonazePAM

Clonazepam is used alone or together with other medicines to treat certain seizure disorders (eg, Lennox-Gastaut syndrome, akinetic, myoclonic, and absence seizures). It is also used to treat panic disorder. Clonazepam is a benzodiazepine that works in the brain to prevent seizures. Benzodiazepines are central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor''s prescription.

Before using Zym-clonazePAM

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of clonazepam in children with seizure disorders. However, safety and efficacy in children with panic disorder have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of clonazepam in the elderly. However, elderly patients are more likely to have confusion and severe drowsiness, or age-related heart, liver, or kidney problems, which may require caution and an adjustment in the dose for patients receiving clonazepam.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Flumazenil

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acepromazine
• Alfentanil
• Alprazolam
• Amobarbital
• Anileridine
• Aripiprazole
• Aripiprazole Lauroxil
• Asenapine
• Baclofen
• Benperidol
• Benzhydrocodone
• Bromazepam
• Bromopride
• Buprenorphine
• Buspirone
• Butabarbital
• Butalbital
• Butorphanol
• Calcifediol
• Calcium Oxybate
• Cannabidiol
• Carbamazepine
• Carbinoxamine
• Carisoprodol
• Carphenazine
• Ceritinib
• Cetirizine
• Chloral Hydrate
• Chlordiazepoxide
• Chlorpromazine
• Chlorzoxazone
• Clarithromycin
• Clobazam
• Clorazepate
• Clozapine
• Codeine
• Cyclobenzaprine
• Dantrolene
• Daridorexant
• Dexmedetomidine
• Diacetylmorphine
• Diazepam
• Dichloralphenazone
• Difenoxin
• Dihydrocodeine
• Diphenhydramine
• Diphenoxylate
• Doxylamine
• Droperidol
• Enflurane
• Esketamine
• Estazolam
• Eszopiclone
• Ethchlorvynol
• Ethopropazine
• Ethylmorphine
• Fentanyl
• Flibanserin
• Flunitrazepam
• Fluphenazine
• Flurazepam
• Fluspirilene
• Fospropofol
• Gabapentin
• Gabapentin Enacarbil
• Halazepam
• Haloperidol
• Halothane
• Hexobarbital
• Hydrocodone
• Hydromorphone
• Hydroxyzine
• Isoflurane
• Ketamine
• Ketazolam
• Ketobemidone
• Ketoconazole
• Lemborexant
• Levocetirizine
• Levorphanol
• Lofexidine
• Lorazepam
• Loxapine
• Magnesium Oxybate
• Meclizine
• Melperone
• Meperidine
• Mephenesin
• Mephobarbital
• Meprobamate
• Meptazinol
• Mesoridazine
• Metaxalone
• Methadone
• Methdilazine
• Methocarbamol
• Methohexital
• Methotrimeprazine
• Methylene Blue
• Metoclopramide
• Midazolam
• Mirtazapine
• Molindone
• Moricizine
• Morphine
• Morphine Sulfate Liposome
• Nalbuphine
• Nicomorphine
• Nitrazepam
• Nitrous Oxide
• Olanzapine
• Opium
• Opium Alkaloids
• Orlistat
• Orphenadrine
• Oxazepam
• Oxycodone
• Oxymorphone
• Papaveretum
• Paregoric
• Pentazocine
• Pentobarbital
• Perampanel
• Perazine
• Periciazine
• Perphenazine
• Phenobarbital
• Pimozide
• Piperacetazine
• Pipotiazine
• Piritramide
• Potassium Oxybate
• Prazepam
• Pregabalin
• Primidone
• Prochlorperazine
• Promazine
• Promethazine
• Propofol
• Quazepam
• Quetiapine
• Ramelteon
• Remifentanil
• Remimazolam
• Remoxipride
• Ropeginterferon Alfa-2b-njft
• Scopolamine
• Secobarbital
• Sertindole
• Sodium Oxybate
• Sufentanil
• Sulpiride
• Suvorexant
• Tapentadol
• Temazepam
• Thiethylperazine
• Thiopental
• Thiopropazate
• Thioridazine
• Tilidine
• Tizanidine
• Tolonium Chloride
• Topiramate
• Tramadol
• Trazodone
• Triazolam
• Trifluoperazine
• Trifluperidol
• Triflupromazine
• Trimeprazine
• Zaleplon
• Zolpidem
• Zopiclone
• Zotepine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Amiodarone
• Desipramine
• Ginkgo
• Nevirapine
• Rifapentine
• Ritonavir
• St John''s Wort
• Theophylline

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

• Ethanol

Other medical problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Alcohol or drug abuse or dependence, or history of or
• Depression, history of or
• Lung or breathing problems or
• Porphyria—Use with caution. May make these conditions worse.

• Glaucoma, narrow angle, acute or
• Liver disease—Should not be used in patients with these conditions.

• Kidney disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper use of Zym-clonazePAM

This section provides information on the proper use of a number of products that contain clonazepam. It may not be specific to Zym-clonazePAM. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is taken for a long time, it may become habit-forming (causing mental or physical dependence).

This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

Swallow the tablet whole with water.

If you are using the disintegrating tablet (wafer), make sure your hands are dry before you handle the tablet. Do not open the blister pack that contains the tablet until you are ready to take it. Remove the tablet from the blister pack by peeling back the foil. Do not push the tablet through the foil. Do not break or split the tablet. Place the tablet in your mouth. It should melt quickly. After the tablet has melted, you may take a sip of water.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor''s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage forms (tablets or disintegrating tablets):
  • For seizures:
    • Adults and children 10 years and older—At first, 0.5 milligram (mg) 3 times per day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 20 mg per day.
    • Children up to 10 years or 30 kilograms (kg) of body weight—Dose is based on body weight and must be determined by your doctor. The dose is usually 0.01 to 0.03 mg per kg of body weight per day, given in 2 or 3 divided doses. However, the dose is usually not more than 0.05 mg per kg of body weight. Your doctor may adjust your dose as needed.
  • For panic disorder:
    • Adults—At first, 0.25 milligram (mg) 2 times per day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 4 mg per day.
    • Children—Use and dose must be determined by your doctor.

Missed dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions while using Zym-clonazePAM

It is very important that your doctor check your progress at regular visits to see if the medicine is working properly and to allow for changes in the dose. Blood tests may be needed to check for unwanted effects.

Tell your doctor if you are pregnant or planning to become pregnant. Using this medicine during the later pregnancy may cause problems in your newborn baby (eg, sedation or withdrawal symptoms). Tell your doctor right away if your baby has an abnormal sleep pattern, diarrhea, feeding problems, a high-pitched cry, irritability, low muscle tone, restlessness, shakiness or tremors, sluggishness, trouble breathing, weight loss, vomiting, or fails to gain weight. If you think you have become pregnant while using the medicine, tell your doctor right away.

This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions.

This medicine may cause drowsiness, trouble with thinking, trouble with controlling movements, or trouble with seeing clearly. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert or able to think or see well.

If you develop any unusual and strange thoughts or behavior while you are taking clonazepam, be sure to discuss it with your doctor. Some changes that have occurred in people taking this medicine are like those seen in people who drink alcohol and then act in a manner that is not normal. Other changes may be more unusual and extreme, such as confusion, worsening of depression, hallucinations (seeing, hearing, or feeling things that are not there), suicidal thoughts, and unusual excitement, nervousness, or irritability.

If you have been taking this medicine for a long time, do not stop taking it without checking first with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help prevent worsening of your condition and reduce the possibility of withdrawal symptoms, including actions that are out of control, anxiety, blurred vision, decreased awareness or responsiveness, discouragement, dizziness, environment seems unreal, feeling of unreality, feeling sad or empty, irritability, lack of appetite, loss of interest or pleasure, mimicry of speech or movements, mutism, negativism, nervousness, peculiar postures or movements, mannerisms or grimacing, seeing, hearing, or feeling things that are not there, sense of detachment from self or body, seizures, severe sleepiness, talking, feeling, and acting with excitement, trouble concentrating and sleeping.

Symptoms of an overdose include: change in consciousness, changes in patterns and rhythms of speech, hallucinations, lack of coordination, loss of consciousness, loss of strength or energy, mood or mental changes, muscle pain or weakness, nightmares, sleepiness or unusual drowsiness, shakiness and unsteady walk, slurred speech, trouble in speaking, trouble sleeping, unsteadiness, trembling, or other problems with muscle control or coordination, unusual drowsiness, dullness, tiredness, weakness or feeling of sluggishness, unusual excitement, nervousness, restlessness, or irritability, or unusual weak feeling. Call your doctor right away if you notice these symptoms.

This medicine will add to the effects of alcohol and other central nervous system (CNS) depressants. CNS depressants are medicines that slow down the nervous system, which may cause drowsiness or make you less alert. Some examples of CNS depressants are antihistamines or medicine for hay fever, allergies or colds, sedatives, tranquilizers, or sleeping medicine, prescription pain medicine or narcotics, barbiturates or seizure medicines, muscle relaxants, or anesthetics (numbing medicines), including some dental anesthetics. Check with your doctor before taking any of these products while you are using this medicine.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Zym-clonazePAM side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Body aches or pain
• chills
• cough
• difficulty breathing
• discouragement
• dizziness
• ear congestion
• feeling sad or empty
• fever
• headache
• irritability
• lack of appetite
• loss of interest or pleasure
• loss of voice
• poor coordination
• runny or stuffy nose
• shakiness and unsteady walk
• sleepiness or unusual drowsiness
• sneezing
• sore throat
• tiredness
• trouble concentrating
• trouble sleeping
• unsteadiness, trembling, or other problems with muscle control or coordination
• unusual tiredness or weakness

Less common

• Being forgetful
• bladder pain
• bloody or cloudy urine
• change in speech
• decrease in frequency of urination
• diarrhea
• difficulty in passing urine
• difficult, burning, or painful urination
• frequent urge to urinate
• general feeling of discomfort or illness
• joint pain
• loss of appetite
• lower back or side pain
• mood or mental changes
• muscle aches and pains
• nausea
• nervousness
• problems in urination or increase in the amount of urine
• shivering
• slurred speech
• sore throat
• sweating
• trouble speaking
• vomiting

Rare

• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• changes in skin color
• chest pain, discomfort, or tightness
• cold sweats
• colds
• confusion
• cough or hoarseness
• difficulty with sleeping
• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• excessive dreaming
• excessive muscle tone
• excitement
• falling
• fast, irregular, pounding, or racing heartbeat or pulse
• feeling mad
• feeling of unreality
• flu-like symptoms
• headache, severe and throbbing
• lack of feeling or emotion
• lack or loss of self-control
• muscle stiffness, tension, or tightness
• nightmares
• pain, inflammation, or swelling in the calves, shoulders, or hands
• pain or swelling in the arms or legs without any injury
• pain, tenderness, or swelling of the foot or leg
• partial or slight paralysis
• scaling
• sense of detachment from self or body
• shakiness in the legs, arms, hands, or feet
• skin rash
• swelling around the eyes
• swelling of the face, ankle, foot, or knees
• thoughts of killing oneself changes in behavior
• trembling or shaking of the hands or feet
• uncaring
• vision changes

Incidence not known

• Anxiety
• black, tarry stools
• bleeding gums
• blood in the urine or stools
• change in consciousness
• chest congestion
• difficulty with coordination
• double vision
• drowsiness
• dry mouth
• feeling that others are watching you or controlling your behavior
• feeling that others can hear your thoughts
• feeling, seeing, or hearing things that are not there
• hyperventilation
• irregular, fast, slow, or shallow breathing
• irregular, twisting uncontrolled movement of the face, hands, arms, or legs
• loss of interest or pleasure
• loss of memory
• loss of strength or energy
• loss of voice
• muscle weakness
• pale or blue lips, fingernails, or skin
• pinpoint red spots on the skin
• problems with memory
• restlessness
• severe mood or mental changes
• sores, ulcers, or white spots on the lips or in the mouth
• stomach pain or fullness
• swollen glands
• trouble breathing
• uncontrolled eye movements
• unusual behavior
• unusual bleeding or bruising
• unusual weakness
• vivid dreams
• weight loss or gain

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Agitation
• change in consciousness
• changes in patterns and rhythms of speech
• confusion
• loss of consciousness
• loss of strength or energy
• mood or mental changes
• nightmares
• shakiness and unsteady walk
• sleepiness or unusual drowsiness
• slurred speech
• talkativeness
• trouble speaking
• unsteadiness, trembling, or other problems with muscle control or coordination
• unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
• unusual excitement, nervousness, restlessness, or irritability
• unusual weak feeling

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Decreased interest in sexual intercourse
• difficulty with swallowing
• dryness or soreness of the throat
• heavy bleeding
• hives
• inability to have or keep an erection
• longer than usual time to ejaculation of semen
• loss in sexual ability, desire, drive, or performance
• pain or tenderness around the eyes and cheekbones
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• voice changes

Rare

• Acid or sour stomach
• ankle, knee, or great toe joint pain
• belching
• bleeding after defecation
• blistering, burning, crusting, dryness, or flaking of the skin
• bloated
• blurred or loss of vision
• change in color perception
• cracks in the skin at the corners of the mouth
• decrease or change in vision
• difficulty moving
• double vision
• dryness of the eyes
• earache
• excess air or gas in stomach or intestines
• feeling of constant movement of self or surroundings
• feeling of warmth
• frequent bowel movements
• full feeling
• hair loss or thinning of the hair
• halos around lights
• heartburn
• increased watering of the mouth
• indigestion
• irregularities in menstruation
• itching in the genital or other skin areas
• itching, scaling, severe redness, soreness, or swelling of the skin
• joint stiffness or swelling
• leg or muscle cramps
• loss of taste
• night blindness
• nosebleeds
• overbright appearance of lights
• pain in the breasts or pelvic area
• pain in the leg, nape, or back
• passing gas
• red, sore eyes
• redness of the face, neck, arms, and occasionally, upper chest
• redness or swelling in the ear
• sensation of spinning
• smaller amount of semen ejaculated than usual
• sore on the edge of the eyelid
• soreness or redness around the fingernails and toenails
• stomach discomfort, upset, or pain
• thickening of the tongue
• thirst
• tooth disorder
• toothache
• tunnel vision
• twitching of the eyes
• uncomfortable swelling around the anus
• worsening of acne

Incidence not known

• Burning feeling in the chest or stomach
• difficulty having a bowel movement (stool)
• increased appetite
• increased hair growth, especially on the face
• increased in sexual ability, desire, drive, or performance
• increased interest in sexual intercourse
• sore gums
• tenderness in the stomach area

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Frequently asked questions

• Klonopin vs Xanax - How are they different?
• Is clonazepam a controlled substance?

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Zymar (Ophthalmic)

Generic name: gatifloxacin (ophthalmic route) [ gat-i-FLOX-a-sin ]
Drug class: Ophthalmic anti-infectives

Medically reviewed by Drugs.com. Last updated on Sep 16, 2022.

Commonly used brand name(s)

In the U.S.

• Zymar
• Zymaxid

Available Dosage Forms:

• Solution

Therapeutic Class: Antibiotic

Chemical Class: Fluoroquinolone

Uses for Zymar

Gatifloxacin eye drops are used to treat infections of the eye, such as bacterial conjunctivitis. Gatifloxacin belongs to a group of medicines called fluoroquinolone antibiotics. It works by killing bacteria that cause conjunctivitis.

This medicine is available only with your doctor''s prescription.

Before using Zymar

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of Zymaxid® in children. However, safety and efficacy have not been established in children younger than 1 year of age.

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of Zymar® in children.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of gatifloxacin eye drops in the elderly.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other medical problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Corneal problems—Use with caution. May make these conditions worse.

Proper use of Zymar

This section provides information on the proper use of a number of products that contain gatifloxacin. It may not be specific to Zymar. Please read with care.

Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to. This medicine is not for long-term use.

To use the eye drops:

• First, wash your hands. Then tilt the head back and pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close the eyes. Do not blink. Keep the eyes closed for 1 or 2 minutes to allow the medicine to come into contact with the infection.
• If you think you did not get the drop of medicine into your eye properly, repeat the directions with another drop.
• To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed.

To help clear up your eye infection completely, keep using this medicine for the full time of treatment, even if your symptoms have disappeared and even if you feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon. Do not miss any doses.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor''s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For ophthalmic dosage form (eye drops):
  • For bacterial conjunctivitis:
    • Zymar®:
      • Adults and children—
        • Days 1 and 2: Put 1 drop in the affected eye every 2 hours while awake, up to 8 times a day.
        • Days 3 through 7: Put 1 drop in the affected eye up to 4 times a day while awake.
    • Zymaxid®:
      • Adults and children 1 year of age and older—
        • Day 1: Put 1 drop in the affected eye every 2 hours while awake, up to 8 times.
        • Days 2 through 7: Put 1 drop in the affected eye 2 to 4 times a day while awake.
      • Children younger than 1 year of age—Use and dose must be determined by your doctor.

Missed dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions while using Zymar

If your or your child''s eye infection does not improve within a few days, or if it becomes worse, check with your doctor.

This medicine may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you or your child have a rash, itching, red or swollen skin around the eye or eyelid, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine.

Serious skin reactions can occur with this medicine. Check with your doctor right away if you or your child have blistering, peeling, or loose skin, red skin lesions, severe acne or skin rash, sores or ulcers on the skin, or fever or chills while you are using this medicine.

Zymar side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Eye irritation
• eye pain
• eye redness

Less common

• Bloody eye
• decrease in vision
• swelling of the membrane covering the white part of the eye

Rare

• Blistering, peeling, or loosening of the skin
• chills
• cough
• diarrhea
• itching
• joint or muscle pain
• red skin lesions, often with a purple center
• red, irritated eyes
• sore throat
• sores, ulcers, or white spots in the mouth or on the lips
• unusual tiredness or weakness

Incidence not known

• Difficulty with swallowing
• dizziness
• fast heartbeat
• hives or welts, or skin rash
• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• redness of the skin
• tightness in the chest
• trouble breathing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Blurred vision
• discharge from the eyes
• itching eyes
• stringy mucus secretions
• swelling of the eye, eyelid, or inner lining of the eyelid
• watering eyes

Less common

• Bad, unusual, or unpleasant (after) taste
• change in taste
• dry eye
• headache

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer