Drug name: Zyncof

Description:

Zyncof

Generic name: dextromethorphan and guaifenesin [ DEX-troe-me-THOR-fan-and-gwye-FEN-e-sin ]
Brand names: Aquatab DM, Broncotron, Coricidin HBP Chest Congestion & Cough, DayQuil Mucus Control DM, Delsym Cough Plus Chest Congestion DM, ... show all 15 brands Fenesin DM IR, G-Zyncof, Mucinex DM, Phlemex, Robitussin Cough + Chest Congestion DM, Safetussin DM, Siltussin DM, TabTussin DM, Tussin DM, Zyncof
Drug class: Upper respiratory combinations

Medically reviewed by Drugs.com on Oct 24, 2022. Written by Cerner Multum.

What is Zyncof?

Dextromethorphan is a cough suppressant. Guaifenesin is an expectorant.

Zyncof is a combination medicine used to treat cough and chest congestion caused by the common cold or allergies.

Dextromethorphan will not treat a cough that is caused by smoking.

There are many brands and forms of this medication available and not all brands are listed on this leaflet.

Zyncof may also be used for purposes not listed in this medication guide.

Warnings

Do not use Zyncof if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Before taking this medicine

Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, and tranylcypromine.

Ask a doctor or pharmacist if this medicine is safe to use if you have:

  • a cough with mucus; or

  • asthma, emphysema, or chronic bronchitis.

Ask a doctor before using this medicine if you are pregnant or breast-feeding.

This medicine may contain phenylalanine. Check the medication label if you have phenylketonuria (PKU).

How should I take Zyncof?

Use exactly as directed on the label, or as prescribed by your doctor. Cold or cough medicine is only for short-term use until your symptoms clear up.

Always follow directions on the medicine label about giving cough or cold medicine to a child. Do not use the medicine only to make a child sleepy. Death can occur from the misuse of cough or cold medicines in very young children.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

You may need to shake the liquid before you measure a dose. Follow all directions on the label.

Swallow the extended-release tablet whole and do not crush, chew, or break it.

Sprinkle the granules directly onto your tongue and swallow right away.

Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking Zyncof.

Call your doctor if your symptoms do not improve after 7 days, or if you have a fever, rash, or headaches.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken this medicine within the past few days.

Store at room temperature away from moisture and heat.

Detailed Zyncof dosage information

What happens if I miss a dose?

Since Zyncof is used when needed, you may not be on a dosing schedule. Skip any missed dose if it''s almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Zyncof?

Avoid driving or hazardous activity until you know how Zyncof will affect you. Your reactions could be impaired.

Drinking alcohol with this medicine can cause side effects.

Ask a doctor or pharmacist before using other cough or cold medicines that may contain similar ingredients.

Zyncof side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

This medicine may cause serious side effects. Stop using this medicine and call your doctor at once if you have:

  • mood changes;

  • severe headache; or

  • severe dizziness or anxiety, feeling like you might pass out;.

Common side effects of Zyncof may include:

  • dizziness, drowsiness;

  • sleep problems (insomnia);

  • diarrhea; or

  • feeling nervous, restless, anxious, or irritable;.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Zyncof side effects (more detail)

What other drugs will affect Zyncof?

Avoid using Zyncof with other drugs that cause drowsiness or slow your breathing (such as opioid medicine, a muscle relaxer, or medicine for anxiety or seizures).

Ask a doctor or pharmacist before using this medicine if you are also using any other drugs, including prescription and over-the-counter medicines, vitamins, and herbal products. Some medicines can cause unwanted or dangerous effects when used together. Not all possible interactions are listed in this medication guide.

Zyncof drug interactions (more detail)

Where can I get more information?

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

More about Zyncof (dextromethorphan / guaifenesin)

  • Check interactions
  • Pricing & coupons
  • Side effects
  • Dosage information
  • During pregnancy
  • Drug class: upper respiratory combinations
  • En español

Patient resources

Other brands

Mucinex DM, Robitussin Cough + Chest Congestion DM, Tussin DM, Mucinex Children''s Cough, ... +14 more

Professional resources

  • Prescribing Information

Related treatment guides

  • Cough
  • Expectoration

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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