Generic name: telotristat ethyl [ tel-OH-tri-stat-ETH-il ]
Drug class: Miscellaneous GI agents

Medically reviewed by Drugs.com on Jun 10, 2021. Written by Cerner Multum.

What is Xermelo?

Xermelo is used in adults to treat carcinoid syndrome diarrhea, in combination with another medicine such as octreotide (Sandostatin).

Xermelo may also be used for purposes not listed in this medication guide.

Warnings

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Before taking this medicine

Tell your doctor if you have ever had liver disease.

Tell your doctor if you are pregnant or breastfeeding.

Not approved for use by anyone younger than 18 years old.

How should I take Xermelo?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Xermelo is usually taken 3 times per day with food.

Xermelo comes in a monthly case that contains 4 weekly boxes; 1 box of 7 daily doses for use each week. Keep each tablet in the package until you are ready to take a dose.

Octreotide is usually given at least 30 minutes after taking Xermelo.

Xermelo is only part of a complete treatment program that may also include other medications. Do not change your doses or medication schedule without your doctor''s advice.

Store at room temperature away from moisture and heat.

Do not share Xermelo with another person, even if they have the same symptoms you have.

What happens if I miss a dose?

Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Xermelo?

Follow your doctor''s instructions about any restrictions on food, beverages, or activity.

Xermelo side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Xermelo may cause serious side effects. Stop using Xermelo and call your doctor at once if you have:

• severe constipation; or

• severe or worsening stomach pain.

Common side effects of Xermelo may include:

• nausea, loss of appetite, gas;

• headache, depressed mood;

• swelling in your hands or feet;

• fever; or

• abnormal liver function tests.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Xermelo?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Other drugs may affect Xermelo, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Where can I get more information?

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Popular FAQ

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Copyright 1996-2023 Cerner Multum, Inc. Version: 3.01.

Xero-Lube

Generic name: saliva substitutes [ sa-LYE-va-SUB-sti-tutes ]
Brand names: Aquoral, Biotene Mouthwash, Caphosol, Glandosane Unflavored, Moi-Stir, ... show all 12 brands NeutraSal, Numoisyn, Optimoist, SalivaMAX, Salivart, Xero-Lube, XyliMelts
Drug class: Mouth and throat products

Medically reviewed by Drugs.com on Aug 29, 2022. Written by Cerner Multum.

What is Xero-Lube?

Xero-Lube are manmade forms of the mucus secretions normally produced in the human mouth. This medicine help to create artificial saliva when the body does not produce enough on its own.

Xero-Lube are used to help relieve dryness and pain or discomfort in the mouth or throat that may be caused by certain disease conditions, medications, surgery, or chemotherapy and radiation treatments.

Xero-Lube may also be used for purposes not listed in this medication guide.

Warnings

There are many brands and forms of saliva substitutes available. Not all brands are listed on this leaflet. Follow all directions on your medicine label and package.

Before taking this medicine

You should not use Xero-Lube if you are allergic to any of the ingredients listed on the product package.

Ask a doctor before using Xero-Lube if you are pregnant or breast-feeding.

How should I use Xero-Lube?

A saliva substitute is for use only in the mouth. Do not get it in your eyes.

Use your saliva substitute product exactly as directed on the label, or as prescribed by your doctor.

Xero-Lube work inside your mouth and are not meant to be swallowed.

To use the oral rinse or other liquid Xero-Lube, swish a small amount in your mouth for 30 seconds, then spit out.

The oral powder must be mixed with about 1 ounce of water before using it. Stir the mixture and use it right away, even if you need to swish 2 or 3 times to get the full amount. Do not save the mixture for later use.

Shake the oral spray gently before each use and spray directly into your mouth and onto your tongue.

The tablet or lozenge can be held in the mouth for long periods of time, even while you are sleeping. Some tablets are pressed onto to your tooth or gums to help hold them in place.

Saliva substitute gel, paste, or swabs may be applied directly onto the gums, tongue, teeth, or sides of the mouth. Follow all instructions carefully.

How often you use a saliva substitute may depend on your condition or your medication schedule.

In most cases, Xero-Lube are used 3 to 5 times per day or whenever your mouth feels dry and uncomfortable. When used during chemotherapy or radiation, you may need to use this medicine up to 10 times per day beginning on or before the day of your treatment. Follow all dosing instructions very carefully.

Do not allow a child to use Xero-Lube without adult supervision.

Xero-Lube may be only part of a complete treatment program that includes using other oral hygiene methods. Follow your doctor''s instructions very closely.

Store your saliva substitute as directed on the product label. Avoid moisture, heat, and light.

What happens if I miss a dose?

Since Xero-Lube are used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

An overdose of a saliva substitute is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed large amounts of this product.

What should I avoid while taking Xero-Lube?

You may need to avoid eating or drinking anything for about 15 minutes after using Xero-Lube. Follow all directions on the label of the product you are using.

Rinse with water if the saliva substitute gets in your eyes.

Xero-Lube side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Xero-Lube?

It is not likely that other drugs you take orally or inject will have an effect on Xero-Lube used in the mouth and not swallowed. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Where can I get more information?

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Copyright 1996-2023 Cerner Multum, Inc. Version: 1.01.