Generic name: cinacalcet [ sin-ah-CAL-set ]
Brand name: Sensipar
Dosage form: oral tablet (30 mg; 60 mg; 90 mg)
Drug class: Calcimimetics

Medically reviewed by Drugs.com on Jul 11, 2022. Written by Cerner Multum.

What is cinacalcet?

Cinacalcet decreases levels of parathyroid hormone (PTH), calcium, and phosphorous in the body.

Cinacalcet is used to treat hyperparathyroidism (overactive functioning of the parathyroid glands) in people who are on long-term dialysis for kidney disease.

Cinacalcet is also used to treat hypercalcemia (high levels of calcium in the blood) in people with cancer of the parathyroid gland, and in people with overactive parathyroid glands that cannot be treated surgically.

Cinacalcet may also be used for purposes not listed in this medication guide.

Warnings

You should not take cinacalcet if you have low levels of calcium in your blood (hypocalcemia).

Before taking this medicine

You should not use cinacalcet if you are allergic to it, or if you have:

• low levels of calcium in your blood (hypocalcemia).

To make sure cinacalcet is safe for you, tell your doctor if you have ever had:

• high or low blood pressure;

• heart disease, heart failure, heart rhythm disorder;

• personal or family history of long QT syndrome;

• a stomach ulcer or severe vomiting;

• liver disease;

• seizures; or

• if you have kidney disease and you are not on dialysis.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether cinacalcet passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are taking this medicine.

Cinacalcet is not approved for use by anyone younger than 18 years old.

How should I take cinacalcet?

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use cinacalcet in larger or smaller amounts or for longer than recommended.

Cinacalcet works best if you take it with food or shortly after eating a meal.

Do not crush or break a cinacalcet tablet. Swallow the pill whole.

To be sure your calcium and phosphorous levels do not get too low, your blood will need to be tested 1 week after you start taking cinacalcet or whenever your dose is changed. You may also need blood tests on a regular basis during treatment.

Store at room temperature away from moisture, light, and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking cinacalcet?

Follow your doctor''s instructions about any restrictions on food, beverages, or activity.

Cinacalcet side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Cinacalcet may cause serious side effects. Call your doctor at once if you have:

• numbness or tingly feeling around your mouth;

• muscle pain, tightness, or contraction;

• a seizure (convulsions);

• shortness of breath (even with mild exertion), swelling, rapid weight gain;

• signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; or

• low levels of calcium in your blood--numbness or tingly feeling around your mouth, fast or slow heart rate, muscle tightness or contraction, overactive reflexes.

Common side effects of cinacalcet may include:

• nausea, vomiting; or

• diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect cinacalcet?

Many drugs can interact with cinacalcet. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Copyright 1996-2023 Cerner Multum, Inc. Version: 7.01.

Medically reviewed by Drugs.com. Last updated on Oct 18, 2022.

What are other common names?

• Cinnamomum aromaticum
• Cinnamomum cassia
• Cinnamomum loureirii
• Cinnamomum ramulus
• Cinnamomum verum
• Cinnamomum zeylanicum
• Bastard Cinnamon
• Canelle
• Canton Cassia
• Casse
• Cassia
• Cassia Aromaticum
• Cassia Bark
• Cassia Cinnamon
• Cassia Lignea
• Ceylon Cinnamon
• Chinese Cassia
• Chinese Cinnamon
• Cinnamomon
• Cinnamomum
• Cinnamon Bark
• Cinnamon Essential Oil
• Cinnamon Flos
• Cinnamonomi Cortex
• False Cinnamon
• Saigon Cinnamon
• True Cinnamon

What is this product used for?

Cinnamon is a spice that is used by some people as medicine. Science does not support the use of this product for any health problem.

What are the precautions when taking this product?

• Always check with your doctor before you use a natural product. Some products may not mix well with drugs or other natural products.

• This product may interfere with some lab tests. Be sure to talk with your doctor about this and all drugs you are taking.

• Do not use this product if you are allergic to the plant Peru balsam.

• Be sure to tell your doctor if you are pregnant, plan on getting pregnant, or are breastfeeding. You will need to talk about the benefits and risks of using this natural product.

• Take extra care if you are taking drugs that are broken down by your liver. This product may increase the harmful effects to your liver.

• If you have blood sugar problems, keep hard candies, glucose tablets, liquid glucose, or juice on hand for low blood sugar.

• Take extra care and check with your doctor if you have:

  • Liver problems

  • Diabetes

What should I watch for?

• Upset stomach

• Sleepy

• Rash or skin redness

When do I need to call the doctor?

• Signs of a very bad reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat. Go to the ER right away.

• Signs of low blood sugar. These include hunger, dizziness, shaking, a fast heartbeat, confusion, or sweating.

• Very bad throwing up

• Very bad loose stools

• Increased heart rate or pulse

• Depressed mood

• Mouth sores

Where can I learn more?

National Center for Complementary and Alternative Medicine

https://nccih.nih.gov/health/cinnamon

Last Reviewed Date

Consumer information use

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Copyright

Copyright © 2023 UpToDate, Inc. and its affiliates and/or licensors. All rights reserved.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer